The VAX2-SERPINE1 axis modulates colorectal cancer cell proliferation and apoptosis through WNT/beta-catenin signaling

Transcription factors (TFs) involve in colorectal cancer (CRC). However, the function and mechanism of VAX2 in the development of CRC remain barely known. In the present study, we observed that transcription factor VAX2 is frequently upregulated in CRC internal sample set and external tissue microar...

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Autors principals:	Jieming Zhang, Guangnan Liu, Siyang Peng, Yidong Chen, Yanci Xie, Yuting Lei, Jieke Wu, Xiaodong Huang, Xiangyang Wei, Linjie Hong, Ping Yang, Ying Peng, Weimei Tang, Xiaosheng Wu, Aimin Li, Side Liu, Xinpeng Shi, Jing Xiong, Jide Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-04-01
Col·lecció:	Translational Oncology
Matèries:	VAX2 SERPINE1 Beta-catenin Colorectal cancer
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S1936523326000409
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