Enforcement of developmental lineage specificity by transcription factor Oct1
Embryonic stem cells co-express Oct4 and Oct1, a related protein with similar DNA-binding specificity. To study the role of Oct1 in ESC pluripotency and transcriptional control, we constructed germline and inducible-conditional Oct1-deficient ESC lines. ESCs lacking Oct1 show normal appearance, self...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications Ltd
2017-05-01
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| Series: | eLife |
| Assuntos: | |
| Acceso en liña: | https://elifesciences.org/articles/20937 |
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