Deubiquitination of DNM1L by USP3 triggers the development and metastasis of gallbladder carcinoma

Abstract Background Patients diagnosed with gallbladder carcinoma (GBC) accompanied by hepatic metastasis exhibit unfavorable prognoses generally. Mitochondrial dysfunction promotes cellular transformation and cancer cell survival implicating its importance in cancer development. Previous studies ha...

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Hauptverfasser:	Ruopeng Liang, Xiaoxue Zhang, Shitao Wu, Jing Liu, Yunpeng Zhai, Chaojie Lin, Zhenya Wang, Yi Zhang, Hao Chen, Rongtao Zhu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-04-01
Schriftenreihe:	Biology Direct
Schlagworte:	DNM1L USP3 Gallbladder cancer Deubiquitination Mitochondrial homeostasis
Online-Zugang:	https://doi.org/10.1186/s13062-025-00637-8
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