Synthesis of <i>N</i>-(3-Acyloxyacyl)glycines, Small Molecules with Potential Role in Gut Microbiome-Endocannabinoidome Communication

The synthesis of some <i>N</i>-(3-acyloxyacyl)glycines, an interesting class of bioactive gut microbiota metabolites, is described. This procedure involves seven reaction steps using the commercially available Meldrum’s acid to obtain highly pure products, in normal or deuterated form. The key point...

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Autori principali:	Rosaria Villano, Vincenzo Di Marzo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-08-01
Serie:	Molecules
Soggetti:	organic synthesis <i>N</i>-(3-acyloxyacyl)glycines <i>N</i>-acyl amino acids gut microbiota metabolites endocannabinoidome
Accesso online:	https://www.mdpi.com/1420-3049/29/15/3703
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