Metal‐Coordinated NIR‐II Nanoadjuvants with Nanobody Conjugation for Potentiating Immunotherapy by Tumor Metabolism Reprogramming

Abstract Immune checkpoint blockade (ICB) immunotherapy remains hampered by insufficient immunogenicity and a high‐lactate immunosuppressive tumor microenvironment (TME). Herein, a nanobody‐engineered NIR‐II nanoadjuvant with targeting metabolic reprogramming capability is constructed for potentiati...

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主要な著者:	Yeneng Dai, Ziang Guo, Dongliang Leng, Guanda Jiao, Kai Chen, Mingxuan Fu, Yang Liu, Qingming Shen, Qi Wang, Lipeng Zhu, Qi Zhao
フォーマット:	Artigo
言語:	Inglês
出版事項:	Wiley 2024-09-01
シリーズ:	Advanced Science
主題:	amplified immunotherapy lactate efflux nanoadjuvants nanobody NIR‐II phototheranostics
オンライン･アクセス:	https://doi.org/10.1002/advs.202404886
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