Identification of IL18/IL18R1 signaling as a predictive biomarker of SGLT2 inhibitor efficacy in type 2 diabetes

Summary: Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are widely used to manage type 2 diabetes mellitus (T2DM) to ameliorate hyperglycemia, albuminuria, and obesity, with established cardiorenal benefits. However, predictive biomarkers for therapeutic responses remain limited. In this study,...

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Egile Nagusiak:	I-Jou Teng, Chien-Hsing Lee, Ying-Chen Chen, Sheng-Chiang Su, Chieh-Hua Lu, Peng-Fei Li, Chia-Luen Huang, Li-Ju Ho, Ming-Hsun Lin, Hsin-Ya Liu, Feng-Chih Kuo
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2025-10-01
Saila:	iScience
Gaiak:	Human metabolism proteomics
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2589004225018553
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