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UBE2E1 Is Preferentially Expressed in the Cytoplasm of Slow-Twitch Fibers and Protects Skeletal Muscles from Exacerbated Atrophy upon Dexamethasone Treatment

Skeletal muscle mass is reduced during many diseases or physiological situations (disuse, aging), which results in decreased strength and increased mortality. Muscle mass is mainly controlled by the ubiquitin-proteasome system (UPS), involving hundreds of ubiquitinating enzymes (E2s and E3s) that ta...

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Wedi'i Gadw mewn:
Prif Awduron: Polge Cécile, Aniort Julien, Armani Andrea, Claustre Agnès, Coudy-Gandilhon Cécile, Tournebize Clara, Deval Christiane, Combaret Lydie, Béchet Daniel, Sandri Marco, Attaix Didier, Taillandier Daniel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2018-11-01
Cyfres:Cells
Pynciau:
ubiquitin-proteasome system
E2 ubiquitin-conjugating enzymes
E3 ubiquitin ligases
UBE2E1
MuRF1
skeletal muscle
atrophy
actin
myosin heavy chain
Mynediad Ar-lein:https://www.mdpi.com/2073-4409/7/11/214
Tagiau: Ychwanegu Tag
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