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Helicobacter pylori Infection Increased Anti-dsDNA and Enhanced Lupus Severity in Symptomatic FcγRIIb-Deficient Lupus Mice

The defect on Fc gamma receptor IIb (FcγRIIb), the only inhibitory FcγR, has been identified as one of the genetic factors increasing susceptibility to lupus. The prevalence of Helicobacter pylori (HP) and FcγRIIb dysfunction-polymorphisms are high among Asians, and their co-existence is possible. U...

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Autors principals: Saowapha Surawut, Wimonrat Panpetch, Jiradej Makjaroen, Pattarin Tangtanatakul, Arthid Thim-Uam, Jutamas Wongphoom, Somying Tumwasorn, Asada Leelahavanichkul
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018-07-01
Col·lecció:Frontiers in Microbiology
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Accés en línia:https://www.frontiersin.org/article/10.3389/fmicb.2018.01488/full
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