Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity

Leukemia, specifically acute myeloid leukemia (AML), is a common malignancy that can be differentiated into multiple subtypes based on leukemogenic history and etiology. Although genetic aberrations, particularly cytogenetic abnormalities and mutations in known oncogenes, play an integral role in AM...

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Hlavní autoři:	Samantha L. Goldman, Ciaran Hassan, Mihir Khunte, Arielle Soldatenko, Yunji Jong, Ebrahim Afshinnekoo, Christopher E. Mason
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2019-03-01
Edice:	Frontiers in Genetics
Témata:	acute myeloid leukemia AML epigenetics heterogeneity epialleles
On-line přístup:	https://www.frontiersin.org/article/10.3389/fgene.2019.00133/full
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