Structure-based virtual screening identified novel FOXM1 inhibitors as the lead compounds for ovarian cancer
Ovarian cancer (OC) is a gynecological tumor with possibly the worst prognosis, its 5-year survival rate being only 47.4%. The first line of therapy prescribed is chemotherapy consisting of platinum and paclitaxel. The primary reason for treatment failure is drug resistance. FOXM1 protein has been f...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Frontiers Media S.A.
2022-11-01
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| Schriftenreihe: | Frontiers in Chemistry |
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| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/fchem.2022.1058256/full |
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