DNA damage and cell death induced by exposure to ultra-high dose rate low-dose pulsed X-rays emitted from a kilojoule plasma focus device

Abstract Background FLASH radiotherapy, characterized by ultra-high dose rates (> 40 Gy/s), potentially spares normal tissues while maintaining antitumor efficacy (the FLASH effect). While electron and proton FLASH are explored, pulsed X-ray sources like plasma focus devices offer unique possibiliti...

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Κύριοι συγγραφείς:	Héctor Araya, Jalaj Jain, Rodrigo Andaur, José Moreno, Sergio Davis, Pablo Diaz, Ethel Velásquez, Josefa Orellana, Martín Ríos, Jessica Toro, Octavio Orellana-Serradell, Cristopher Fierro, Leopoldo Soto, Katherine Marcelain
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2026-03-01
Σειρά:	Biological Research
Θέματα:	FLASH radiation Cancer Colorectal cancer DNA damage Cell death Plasma focus device
Διαθέσιμο Online:	https://doi.org/10.1186/s40659-026-00674-1
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