Glycyrrhizin arginine salt protects against cisplation-induced acute liver injury by repressing BECN1-mediated ferroptosis

The study aimed to investigate the protective effects and biological mechanisms of glycyrrhizin arginine salt (Gly-Arg) against cisplatin (Cis)-induced liver injury. Our data showed that Gly-Arg improved Cis-induced liver injury. Further study showed that BECN1 (beclin1) and LC3-II/LC3-I protein exp...

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Autors principals:	Jun Guo, Jiameng Yin, Pu Liu, Xin Zhang, Jie Wei, Mingjun Wang, Yanxia Xiao, Yongzhan Zhen, Yajun Lin, Jian Li
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-09-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	glycyrrhizin arginine salt cisplatin liver injury BECN1-xCT complex ferroptosis
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1219486/full
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