Molecular identification of hyaluronate lyase, not hyaluronidase, as an intrinsic hyaluronan-degrading enzyme in Clostridium perfringens strain ATCC 13124
Abstract Clostridium perfringens, an opportunistic pathogen, produces mu-toxin hyaluronidases including endo-β-N-acetylglucosaminidases (Nags) as a virulence invasion factor. To clarify an intrinsic factor for degradation of host extracellular hyaluronan, we focused on hyaluronate lyase (HysA), dist...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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Nature Portfolio
2024-10-01
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| Serie: | Scientific Reports |
| Accesso online: | https://doi.org/10.1038/s41598-024-73955-y |
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