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The swine acute diarrhea syndrome coronavirus spike protein promotes syncytial formation via upregulation of cellular cholesterol synthesis

ABSTRACT Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a novel coronavirus that causes acute diarrhea, vomiting, and high mortality in suckling piglets. Research has demonstrated that certain viruses enhance their replication by modulating intracellular cholesterol metabolism. However, the...

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主要な著者: Dakai Liu, Miaomiao Zeng, Jiyu Zhang, Liaoyuan Zhang, Hongyan Shi, Xin Zhang, Jialin Zhang, Jianfei Chen, Zhaoyang Ji, Xiuwen Li, Gengting Gu, Tingshuai Feng, Da Shi, Dongbo Sun, Li Feng
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2025-08-01
シリーズ:mBio
主題:
オンライン・アクセス:https://journals.asm.org/doi/10.1128/mbio.00976-25
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