Identification of boholamide A analogue as a potential hypoxia-selective anti-triple-negative breast cancer agent by targeting eEF1A1

Triple-negative breast cancer (TNBC) is one of the most aggressive and metastatic forms of breast cancer, for which there are currently no satisfactory therapeutic agents. Here, we reported for the first time that boholamide A, a naturally occurring macrocyclic depsipeptide, exhibited hypoxia-select...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Guangju Liu, Fengyuan Zhang, Fangzhi Han, Sisi Chen, Junjie Ou, Renfeng Qiao, Yixuan Jiang, Shaojie Miao, Wei Lin, Yahui Ding, Quan Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-05-01
coleção:	Acta Pharmaceutica Sinica B
Assuntos:	Boholamide A analogue Hypoxia selectivity eEF1A1 Triple-negative breast cancer
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211383526001115
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!