Atg2 coordinates microbial metabolite signaling and epigenetic remodeling to maintain intestinal lipid homeostasis in Drosophila
Abstract Background The autophagy-related protein Atg2 maintains intestinal homeostasis by preventing lipid accumulation and microbial dysbiosis; however, the mechanisms by which these pathologies interconnect remain unknown. Results We identify a microbiota‒metabolite‒epigenome axis through which A...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BMC
2026-03-01
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| Collection: | Microbiome |
| Sujets: | |
| Accès en ligne: | https://doi.org/10.1186/s40168-026-02356-2 |
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