TLR-4 and CD14 Genotypes and Soluble CD14: Could They Predispose to Coronary Atherosclerosis?

Background: Inflammatory mechanisms are key to the pathogenesis of atherosclerosis. Functional polymorphisms of TLR-4, Asp299Gly and Thr399Ile, CD14 promoter area C260T polymorphism and plasma levels of soluble CD14 are studied in subjects with Coronary Artery Disease (CAD). Methods: DNA was obtaine...

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Detalhes bibliográficos

Principais autores:	Maria Kalliopi Konstantinidou, Nikos Goutas, Dimitrios Vlachodimitropoulos, Antigoni Chaidaroglou, Demetrios Stefanou, Nikoleta Poumpouridou, Renata Mastorakou, Maria Gazouli, Dimitrios Kyparissopoulos, Chara Spiliopoulou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2016-03-01
coleção:	Journal of Cardiovascular Development and Disease
Assuntos:	coronary atheroscerosis coronary artery disease Toll-Like-Receptor 4 (TLR-4) CD14 sCD14 PCR-RFLP ELISA
Acesso em linha:	http://www.mdpi.com/2308-3425/3/1/9
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