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Enhanced Stability of DNA Oligonucleotides with Partially Zwitterionic Backbone Structures in Biological Media

Deficient stability towards nuclease-mediated degradation is one of the most relevant tasks in the development of oligonucleotide-derived biomedical agents. This hurdle can be overcome through modifications to the native oligonucleotide backbone structure, with the goal of simultaneously retaining t...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Melissa Meng, Boris Schmidtgall, Christian Ducho
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: MDPI AG 2018-11-01
Цуврал:Molecules
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/1420-3049/23/11/2941
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