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The Influence of Dimerization on the Pharmacokinetics and Activity of an Antibacterial Enzyme Lysostaphin

The increasing prevalence of antibiotic-resistant strains of pathogenic bacteria is a major healthcare problem. Antibacterial lysins are enzymes that cleave the peptidoglycan of the bacterial cell wall. These proteins hold potential as a supplement or an alternative to traditional antibiotics since...

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Principais autores: Alexander V. Grishin, Natalia V. Lavrova, Alexander M. Lyashchuk, Natalia V. Strukova, Maria S. Generalova, Anna V. Ryazanova, Nikita V. Shestak, Irina S. Boksha, Nikita B. Polyakov, Zoya M. Galushkina, Lyubov A. Soboleva, Sergey S. Vetchinin, Vitaliy M. Pavlov, Anna S. Karyagina, Vladimir G. Lunin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-05-01
coleção:Molecules
Assuntos:
antibiotic resistance
endolysin
lysin
lysostaphin
dimerization
pharmacokinetics
staphylococcus
Acesso em linha:https://www.mdpi.com/1420-3049/24/10/1879
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