Sex disparities in hepatocellular carcinoma immunotherapy: hormonal and genetic influences on treatment efficacy

Hepatocellular carcinoma (HCC) is a highly aggressive liver cancer with a rising incidence globally. Immunotherapy, particularly immune checkpoint inhibitors (ICIs), has revolutionized HCC treatment, yet response rates remain variable. Sex-based disparities in immunotherapy efficacy have become incr...

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Hlavní autoři:	Lei Song, Liyan Sun, Yuning Ren, Xiaodan Wang, Lei Xian
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-05-01
Edice:	Frontiers in Immunology
Témata:	sex disparities immunotherapy hepatocellular carcinoma estrogen hormone
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1607374/full
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