Allele-specific vitamin D receptor binding is associated with pediatric-onset multiple sclerosis

Background and Objectives The genetic basis of adult-onset multiple sclerosis (MS) is well-studied, but less is known about pediatric-onset MS (pedMS), comprising approximately 5% of all MS onsets. Mendelian randomization (MR) studies have demonstrated evidence for a causal association between MS an...

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Auteurs principaux:	Defne Yilmaz, Cameron Adams, Mary K Horton, Jennifer S Graves, Carla Francisco, Alice Edwards, Hong Quach, Diana Quach, Gregory Aaen, Timothy Lotze, Soe Mar, Jayne Ness, Yolanda Wheeler, Mark P Gorman, Leslie Benson, Bianca Weinstock-Guttman, Amy Waldman, Teri Schreiner, Jan-Mendelt Tillema, Tanuja Chitnis, John Rose, T Charles Casper, Mary Rensel, Emmanuelle Waubant, Lisa F Barcellos
Format:	Artigo
Langue:	Inglês
Publié:	SAGE Publishing 2025-04-01
Collection:	Multiple Sclerosis Journal - Experimental, Translational and Clinical
Accès en ligne:	https://doi.org/10.1177/20552173251335625
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