The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

Epithelial-to-Mesenchymal Transition (EMT) has been shown to be crucial in tumorigenesis where the EMT program enhances metastasis, chemoresistance and tumor stemness. Due to its emerging role as a pivotal driver of tumorigenesis, targeting EMT is of great therapeutic interest in counteracting metas...

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Autori principali:	Chin-Yap Loh, Jian Yi Chai, Ting Fang Tang, Won Fen Wong, Gautam Sethi, Muthu Kumaraswamy Shanmugam, Pei Pei Chong, Chung Yeng Looi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2019-09-01
Serie:	Cells
Soggetti:	E-cadherin N-cadherin Epithelial-to-Mesenchymal Transition signaling pathways natural compounds
Accesso online:	https://www.mdpi.com/2073-4409/8/10/1118
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