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The inflammatory injury in the striatal microglia-dopaminergic-neuron crosstalk involved in Tourette syndrome development

BackgroundTourette syndrome (TS) is associated with immunological dysfunction. The DA system is closely related to TS development, or behavioral stereotypes. Previous evidence suggested that hyper-M1-polarized microglia may exist in the brains of TS individuals. However, the role of microglia in TS...

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Principais autores: Xueming Wang, Xiumei Liu, Liangliang Chen, Xiaoling Zhang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178113/full
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