LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior
Lamins form stable filaments at the nuclear periphery in metazoans. Unlike B-type lamins, lamins A and C localize also in the nuclear interior, where they interact with lamin-associated polypeptide 2 alpha (LAP2α). Using antibody labeling, we previously observed a depletion of nucleoplasmic A-type l...
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| Principais autores: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications Ltd
2021-02-01
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| 叢編: | eLife |
| 主題: | |
| 在線閱讀: | https://elifesciences.org/articles/63476 |
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