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LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior

Lamins form stable filaments at the nuclear periphery in metazoans. Unlike B-type lamins, lamins A and C localize also in the nuclear interior, where they interact with lamin-associated polypeptide 2 alpha (LAP2α). Using antibody labeling, we previously observed a depletion of nucleoplasmic A-type l...

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Príomhchruthaitheoirí: Nana Naetar, Konstantina Georgiou, Christian Knapp, Irena Bronshtein, Elisabeth Zier, Petra Fichtinger, Thomas Dechat, Yuval Garini, Roland Foisner
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: eLife Sciences Publications Ltd 2021-02-01
Sraith:eLife
Ábhair:
Rochtain ar líne:https://elifesciences.org/articles/63476
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