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Palmitoylcarnitine impairs immunity in decompensated cirrhosis

Background & Aims: In patients with cirrhosis, acute decompensation (AD) correlates with a hyperinflammatory state driven by mitochondrial dysfunction, which is a significant factor in the progression toward acute-on-chronic liver failure (ACLF). Elevated circulating levels of acylcarnitine, ind...

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Guardat en:
Autors principals: Ingrid Wei Zhang, María Belén Sánchez-Rodríguez, Cristina López-Vicario, Mireia Casulleras, Marta Duran-Güell, Roger Flores-Costa, Ferran Aguilar, Michael Rothe, Paula Segalés, Carmen García-Ruiz, José C. Fernández-Checa, Jonel Trebicka, Vicente Arroyo, Joan Clària
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2024-11-01
Col·lecció:JHEP Reports
Matèries:
Immune cells
Acute decompensation of cirrhosis
Acylcarnitines
Mitochondrial dysfunction
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2589555924001915
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