Changes in glucose-induced plasma active glucagon-like peptide-1 levels by co-administration of sodium–glucose cotransporter inhibitors with dipeptidyl peptidase-4 inhibitors in rodents

We investigated whether structurally different sodium–glucose cotransporter (SGLT) 2 inhibitors, when co-administered with dipeptidyl peptidase-4 (DPP4) inhibitors, could enhance glucagon-like peptide-1 (GLP-1) secretion during oral glucose tolerance tests (OGTTs) in rodents. Three different SGLT in...

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Bibliografske podrobnosti

Principais autores:	Takahiro Oguma, Chiaki Kuriyama, Keiko Nakayama, Yasuaki Matsushita, Kumiko Hikida, Minoru Tsuda-Tsukimoto, Akira Saito, Kenji Arakawa, Kiichiro Ueta, Masabumi Minami, Masaharu Shiotani
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2016-12-01
Serija:	Journal of Pharmacological Sciences
Teme:	SGLT2 inhibitor DPP4 inhibitor Canagliflozin Combination treatment Glucagon-like peptide-1
Online dostop:	http://www.sciencedirect.com/science/article/pii/S1347861316301372
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