Designing a potent multivalent epitope vaccine candidate against Orientia tsutsugamushi via reverse vaccinology technique - bioinformatics and immunoinformatic approach

Scrub typhus is a life-threatening, undifferentiated febrile illness caused by a gram-negative bacterium, Orientia tsutsugamushi. The bacterial strain is a global health concern that should be considered. Despite several years of effort for the development of an effective immunogenic vaccine, no suc...

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Bibliografiska uppgifter

Huvudupphov:	Subhasmita Panda, Subrat Kumar Swain, Basanta Pravas Sahu, Soumya Ranjan Mahapatra, Jyotirmayee Dey, Rachita Sarangi, Anu Vinod Ranade, Namrata Mishra
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Frontiers Media S.A. 2025-02-01
Serie:	Frontiers in Immunology
Ämnen:	multiplex vaccinology scrub typhus protein-protein docking immune simulation in-silico cloning molecular dynamic simulation
Länkar:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1513245/full
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