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Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1

Abstract Na+/Ca2+ exchangers (NCX) transport Ca2+ in or out of cells in exchange for Na+. They are ubiquitously expressed and play an essential role in maintaining cytosolic Ca2+ homeostasis. Although extensively studied, little is known about the global structural arrangement of eukaryotic NCXs and...

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Hlavní autoři: Jing Xue, Weizhong Zeng, Yan Han, Scott John, Michela Ottolia, Youxing Jiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2023-10-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-023-41885-4
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