Mesenchymal stromal cell therapy for systemic lupus erythematosus: mechanisms, clinical translation, and future directions

Abstract Systemic Lupus Erythematosus (SLE) is a complex autoimmune condition, fundamentally characterized by the loss of self-tolerance. This breakdown leads to the generation of autoantibodies and widespread inflammation that compromises multiple organs. A significant clinical challenge in SLE man...

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Principais autores:	Shuaijie Ding, Shiyi Wu, Yunan Cui, Yixin Zhou, Sheng Qiu, Zhi Ye, Ruitian Ma, Yixuan Wang Wan, Zhenhua Ying
格式:	Artigo
語言:	Inglês
出版:	BMC 2026-06-01
叢編:	Stem Cell Research & Therapy
主題:	Systemic lupus erythematosus Mesenchymal stromal cell Immunomodulation Cell therapy Cell engineering modifications Clinical translation
在線閱讀:	https://doi.org/10.1186/s13287-026-05058-6
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