Non-operative management after chemoradiotherapy plus consolidation or sandwich (induction with bevacizumab and consolidation) chemotherapy in patients with locally advanced rectal cancer: a multicentre, randomised phase II trial (NOMINATE trial)

Introduction Total mesorectal excision (TME) and postoperative adjuvant chemotherapy following neoadjuvant chemoradiotherapy (CRT) is the standard treatment for locally advanced rectal cancer (LARC). However, neoadjuvant CRT has no recognised impact on reducing distant recurrence, and patients suffe...

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Váldodahkkit:	Koji Okabayashi, Eiji Shinozaki, Kensei Yamaguchi, Tomohiro Yamaguchi, Naoki Ishizuka, Tsuyoshi Konishi, Takashi Akiyoshi, Senzo Taguchi, Akiko Chino, Makiko Hiratsuka, Tetsuro Tominaga, Takashi Nonaka, Shigeo Toda, Shuichiro Matoba, Shimpei Matsui, Toshiki Mukai, Yukiharu Hiyoshi, Toshiya Nagasaki, Masashi Ueno, Hiroya Kuroyanagi, Yosuke Fukunaga
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMJ Publishing Group 2022-03-01
Ráidu:	BMJ Open
Liŋkkat:	https://bmjopen.bmj.com/content/12/3/e055140.full
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