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SPARC Promotes Aerobic Glycolysis and 5‐Fluorouracil Resistance in Colorectal Cancer Through the STAT3/HK2 Axis

ABSTRACT Background Chemotherapy has been used extensively in the clinic to treat colorectal cancer (CRC). Nevertheless, cancer cells usually develop chemoresistance under chemotherapy stress, leading to treatment failure. At present, the mechanism of chemoresistance in patients with CRC is not full...

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Autors principals: Jingrong Xiang, Huan Zhang, Kanger Shen, Jie Feng, Kexi Yang, Tongguo Shi, Qinhua Xi
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2025-06-01
Col·lecció:Cancer Medicine
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Accés en línia:https://doi.org/10.1002/cam4.70972
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