DNA polymerase ε relies on a unique domain for efficient replisome assembly and strand synthesis
DNA polymerase epsilon (Pol ε) synthesizes half of the genome in every cell cycle. Here the authors uncover a dual role of a unique domain within the Pol ε catalytic core in replisome assembly and DNA synthesis and the impact of this domain on genome stability.
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2020-05-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-020-16095-x |
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