Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways.

Resuscitation with 0.9% Normal Saline (NS), a non-buffered acidic solution, leads to increased morbidity and mortality in the critically ill. The goal of this study was to determine the molecular mechanisms of endothelial injury after exposure to NS. The hypothesis of this investigation is that expo...

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מידע ביבליוגרפי

Principais autores:	Joyce Cheung-Flynn, Bret D Alvis, Kyle M Hocking, Christy M Guth, Weifeng Luo, Reid McCallister, Kalyan Chadalavada, Monica Polcz, Padmini Komalavilas, Colleen M Brophy
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Public Library of Science (PLoS) 2019-01-01
סדרה:	PLoS ONE
גישה מקוונת:	https://doi.org/10.1371/journal.pone.0220893
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!