Naltrexone aversion and treatment efficacy are greatest in humans and rats that actively consume high levels of alcohol
The opioid antagonist naltrexone is the standard pharmacotherapy for alcoholism, although compliance is often low. The mechanism by which naltrexone reduces drinking is yet unclear. Here we show that in active alcoholics the magnitude of naltrexone treatment efficacy is correlated with the level of...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2009-01-01
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| Colecção: | Neurobiology of Disease |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S096999610800226X |
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