Toward Precision Dosing of Lamotrigine During Pregnancy: Physiologically Based Pharmacokinetic Modeling and Simulation
ABSTRACT Lamotrigine is a commonly used anti‐seizure medication in pregnant women. However, its pharmacokinetics (PK) during pregnancy markedly change, increasing the frequency of seizures and endangering the safety of the mother and fetus. Meanwhile, insufficient PK data on lamotrigine during pregn...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Wiley
2025-05-01
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| Σειρά: | CPT: Pharmacometrics & Systems Pharmacology |
| Θέματα: | |
| Διαθέσιμο Online: | https://doi.org/10.1002/psp4.70007 |
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