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Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys

Huntington's disease (HD) results from degeneration of striatal neurons. Choroid plexus (CP) cells secrete neurotrophic factors, and CP transplants are neuroprotective in rat models of HD. To determine if similar neuroprotective effects could be obtained in primates, porcine CP was encapsulated in a...

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Автори: Dwaine F. Emerich, Christopher G. Thanos, Moses Goddard, Stephen J.M. Skinner, Marilyn S. Geany, William J. Bell, Briannan Bintz, Patricia Schneider, Yaping Chu, Rangasamy Suresh Babu, Cesario V. Borlongan, Kim Boekelheide, Susan Hall, Bronwyn Bryant, Jeffrey H. Kordower
Формат: Artigo
Мова:Inglês
Опубліковано: Elsevier 2006-08-01
Серія:Neurobiology of Disease
Предмети:
Choroid plexus
CNS transplantation
Alginate
Encapsulation
Neuroprotection
Онлайн доступ:http://www.sciencedirect.com/science/article/pii/S0969996106000891
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