scVAR: integrating genomics and transcriptomics from single-cell RNA-seq —insights from leukemia case studies

The advent of high-throughput technologies has accelerated biomedical research by facilitating the investigation of biological complexity at unprecedented resolution. Single-cell RNA sequencing (scRNA-seq) has transformed our ability to deconstruct cellular heterogeneity in complex diseases. Acute m...

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Detalhes bibliográficos

Principais autores:	Ludovica Celli, Samuele Manessi, Matteo Barcella, Ivan Merelli
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-01-01
coleção:	Frontiers in Genetics
Assuntos:	genetic heterogeneity leukemia multi-omics integration single-cell RNA sequencing variational autoencoder
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fgene.2025.1604484/full
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