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Strong nuclear EGFR expression in colorectal carcinomas is associated with cyclin-D1 but not with gene EGFR amplification

<p>Abstract</p> <p>Background</p> <p>Prognostic and predictive significance of epidermal growth factor receptor (EGFR) in colorectal carcinomas (CRCs) is still controversial. The aim of the present study was to explore and correlate membrane and nuclear EGFR and cyclin-D1 protein expression with EGF...

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Hlavní autoři: Dekanić Andrea, Dobrila Dintinjan Renata, Budisavljević Ivana, Pećanić Sanja, Žuvić Butorac Marta, Jonjić Nives
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2011-11-01
Edice:Diagnostic Pathology
Témata:
colorectal carcinoma
nuclear EGFR
cyclin-D1
On-line přístup:http://www.diagnosticpathology.org/content/6/1/108
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