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Hyperoxidation of Peroxiredoxins and Effects on Physiology of <i>Drosophila</i>

The catalytic activity of peroxiredoxins (Prx) is determined by the conserved peroxidatic cysteine (Cys<sub>P</sub>), which reacts with peroxides to form sulfenic acid (Cys-SOH). Under conditions of oxidative stress, Cys<sub>P</sub> is oxidized to catalytically inactive sulfinic (Cys-SO<sub>2</sub>)...

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Bibliografiske detaljer
Principais autores: Austin McGinnis, Vladimir I. Klichko, William C. Orr, Svetlana N. Radyuk
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-04-01
Serier:Antioxidants
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Online adgang:https://www.mdpi.com/2076-3921/10/4/606
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