Antagonism versus cooperativity with TALE cofactors at the base of the functional diversification of Hox protein function.

Extradenticle (Exd) and Homothorax (Hth) function as positive transcriptional cofactors of Hox proteins, helping them to bind specifically their direct targets. The posterior Hox protein Abdominal-B (Abd-B) does not require Exd/Hth to bind DNA; and, during embryogenesis, Abd-B represses hth and exd...

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Bibliografiske detaljer

Principais autores:	María Luisa Rivas, Jose Manuel Espinosa-Vázquez, Nagraj Sambrani, Stephen Greig, Samir Merabet, Yacine Graba, James Castelli-Gair Hombría
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2013-01-01
Serier:	PLoS Genetics
Online adgang:	http://europepmc.org/articles/PMC3567137?pdf=render
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