The role of acetylcholine and its receptors in tumor immune regulation: mechanisms and potential therapeutic targets

Abstract Acetylcholine (ACh) is an essential neurotransmitter that has recently gained attention for its multifunctional role in tumor immune regulation. By binding neuronal loss to nicotinic and muscarinic receptors, ACh directly promotes tumor cell proliferation and migration while modulating immu...

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Detalhes bibliográficos

Principais autores:	Chunyu Zhang, Xiangdong Guo, Yanan Wang, Shuo Zhang, Zhihua Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-09-01
coleção:	Molecular Cancer
Assuntos:	Acetylcholine Tumor immunity Nicotinic acetylcholine receptor Muscarinic acetylcholine receptor
Acesso em linha:	https://doi.org/10.1186/s12943-025-02441-4
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