Maturation of human induced pluripotent stem cell-derived cardiomyocytes promoted by Brachyury priming
Abstract Cardiac differentiation of human induced pluripotent stem cells is readily achievable, yet derivation of mature cardiomyocytes has been a recognized limitation. Here, a mesoderm priming approach was engineered to boost the maturation of cardiomyocyte progeny derived from pluripotent stem ce...
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| Principais autores: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2025-04-01
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| Serier: | Scientific Reports |
| Online adgang: | https://doi.org/10.1038/s41598-025-97676-y |
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