The Genome Sequence of the Eastern Woodchuck (Marmota monax) – A Preclinical Animal Model for Chronic Hepatitis B

The Eastern woodchuck (Marmota monax) has been extensively used in research of chronic hepatitis B and liver cancer because its infection with the woodchuck hepatitis virus closely resembles a human hepatitis B virus infection. Development of novel immunotherapeutic approaches requires genetic infor...

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Autors principals:	Tyler S. Alioto, Fernando Cruz, Jèssica Gómez-Garrido, Miriam Triyatni, Marta Gut, Leonor Frias, Anna Esteve-Codina, Stephan Menne, Anna Kiialainen, Nadine Kumpesa, Fabian Birzele, Roland Schmucki, Ivo G. Gut, Olivia Spleiss
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2019-12-01
Col·lecció:	G3: Genes, Genomes, Genetics
Matèries:	eastern woodchuck marmota monax chronic hepatitis b hepatocellular carcinoma immune response whole genome sequencing genome assembly
Accés en línia:	http://g3journal.org/lookup/doi/10.1534/g3.119.400413
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