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Study of Iron Piperazine-Based Chelators as Potential Siderophore Mimetics

Gram-negative bacteria&#8217;s resistance such as <i>Pseudomonas aeruginosa</i> and the <i>Burkholderia</i> group to conventional antibiotics leads to therapeutic failure. Use of siderophores as Trojan horses to internalize antibacterial agents or toxic metals within bacteria is a promising strategy...

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Autori principali: Pauline Loupias, Isabelle Dechamps-Olivier, Laurent Dupont, Pierre Vanlemmens, Catherine Mullié, Nicolas Taudon, Anne Bouchut, Alexandra Dassonville-Klimpt, Pascal Sonnet
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2019-10-01
Serie:Pharmaceuticals
Soggetti:
<i>pseudomonas</i> group
siderophore mimetics
chelators
iron
piperazine
Accesso online:https://www.mdpi.com/1424-8247/12/4/160
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