Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors

Claudin18.2 (CLDN18.2) is a tight junction protein that is overexpressed in a variety of solid tumors such as gastrointestinal cancer and oesophageal cancer. It has been identified as a promising target and a potential biomarker to diagnose tumor, evaluate efficacy, and determine patient prognosis....

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Bibliografische Detailangaben

Hauptverfasser:	Yan Chen, Xingguo Hou, Dapeng Li, Jin Ding, Jiayue Liu, Zilei Wang, Fei Teng, Hongjun Li, Fan Zhang, Yi Gu, Steven Yu, Xueming Qian, Zhi Yang, Hua Zhu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-04-01
Schriftenreihe:	Journal of Pharmaceutical Analysis
Schlagworte:	Claudin18.2 Gastrointestinal cancers Zirconium-89 Positron emission tomography Good Manufacturing Practices
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2095177923000357
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