Bone-edge electroacupuncture relieves pain by regulating expression of GRK5, β-arrestin 2 and PKCα proteins in locus coeruleus in bone cancer pain rats with morphine tolerance

Objective To observe the effect of bone-edge electroacupuncture(EA) intervention on mechanical pain threshold(PT) and expression of G protein-coupled receptor kinase(GRK5), β-arrestin 2, total and phosphorylated PKC alpha(p-PKCα) proteins in the locus coeruleus(LC) of rats with bone cancer pain indu...

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Bibliografische Detailangaben

Hauptverfasser:	DU Jun-ying, CHEN Feng, JIANG Bin, FU Tao-fang, FANG Jian-qiao, LIANG Yi
Format:	Artigo
Sprache:	Chinês
Veröffentlicht:	Editorial Office of Acupuncture Research 2020-01-01
Schriftenreihe:	针刺研究
Schlagworte:	Morphine tolerance Electroacupuncture analgesia Bone-edge acupoint Locus coeruleus PKCα G protein-coupled receptor kinase(GRK5) β-arrestin 2
Online-Zugang:	http://www.zhenciyanjiu.cn/thesisDetails#10.13702/j.1000-0607.190003
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