Generation of HLA Universal Megakaryocytes and Platelets by Genetic Engineering
Patelet transfusion refractoriness remains a relevant hurdle in the treatment of severe alloimmunized thrombocytopenic patients. Antibodies specific for the human leukocyte antigens (HLA) class I are considered the major immunological cause for PLT transfusion refractoriness. Due to the insufficient...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021-10-01
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| Colecção: | Frontiers in Immunology |
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| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.768458/full |
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