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Sample Size Reassessment and Hypothesis Testing in Adaptive Survival Trials.

Mid-study design modifications are becoming increasingly accepted in confirmatory clinical trials, so long as appropriate methods are applied such that error rates are controlled. It is therefore unfortunate that the important case of time-to-event endpoints is not easily handled by the standard the...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Dominic Magirr, Thomas Jaki, Franz Koenig, Martin Posch
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Public Library of Science (PLoS) 2016-01-01
Цуврал:PLoS ONE
Онлайн хандалт:https://doi.org/10.1371/journal.pone.0146465
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