Protective Effect of α-Lipoic Acid Against Arsenic Trioxide–Induced Acute Cardiac Toxicity in Rats

The clinical use of arsenic trioxide (ATO) is often limited because of its adverse effects. We examined whether α-lipoic acid (LA) protects against the ATO-induced cardiac toxicity. In the chronic study, two of four rats suddenly died by the repeated dosing of ATO, whereas no deaths were observed in...

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Autores principales:	Masafumi Kumazaki, Hitoshi Ando, Akira Sasaki, Taka-aki Koshimizu, Kentarou Ushijima, Keiko Hosohata, Yasuo Oshima, Akio Fujimura
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2011-01-01
Colección:	Journal of Pharmacological Sciences
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S1347861319307923
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